Background Methotrexate (MTX) is well known to affect folic acid metabolism, so MTX treatment can result in alterations of mean corpuscular volume (MCV), which may impact on red cell distribution width (RDW), as MCV levels feed into RDW calculation. We thus questioned whether RDW levels and subsequently its diagnostic utility in RA subjects, as reported before, are influenced by ongoing MTX Mean corpuscular volume measures the average volume of red blood cells. Smaller red blood cells (low MCV) are microcytic. This can result from inadequate iron intake or excess bleeding. Larger red blood cells (high MCV) are macrocytic. This is typically caused by the release of immature red blood cells due to a folate or vitamin B12 deficiency. Anemia can be classified according to mean corpuscular volume (MCV), a measure of the average volume of RBCs in a specimen. Low MCV indicates microcytic, normal MCV indicates normocytic, and high MCV indicates macrocytic. Anemia is generally defined as hemoglobin of less than 13.0 g/dL in men and less than 12.0 g/dL in premenopausal women The typical ranges are: What does it mean if my MCH is low? An MCH value calculated below 27.5 pg is considered low MCH. This means that there’s a low amount of hemoglobin present per Pancytopenia is a condition where you have too few red blood cells, white blood cells, and platelets. It can cause symptoms like fatigue, dizziness, and fever. Your body has three types of blood Normal Ranges. What Low Values Mean. Hematocrit (HCT) and hemoglobin (Hb) are two blood tests used to detect abnormalities in your red blood cells (RBCs). Hematocrit is the percentage of RBCs in your blood, while hemoglobin is a protein in RBCs that carries oxygen to cells. The HCT and Hb values are reported as part of a complete blood count FWnx. Determinations of the hemoglobin level, hematocrit, MCV, white blood cell count, a flow-cytometric differential, serum ferritin, and TS were a routine part of the appraisal of these patients. Consequently, about 99% of the hemoglobin, hematocrit, MCV, white blood cell count, differential, and TS values were recorded, and serum ferritin values The RBC MCV is a measure of the average volume of the RBCs in a given blood sample. The MCV is typically calculated from the RBC histogram, which is plotted by the hematology analyzer ( Fig. 25.4A ). The x -axis of the histogram corresponds to the RBC volume, measured in fL, and the y -axis corresponds to the percentage of RBCs at each specific RESULTS: This study shows that hyperglyce-mia increases the red blood cells count, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglo-bin concentration (MCHC). Red blood cell dis-tribution width (RDW) was negatively correlat-ed with poor glycemic control. Concurrently, the presence of micro and

high red blood cell count but low mcv and mch